In a series of recent clinical studies approved by the Sapienza University of Rome ethics committee, an Italian research group provided preliminary evidence on the short-term beneficial effect of extra virgin olive oil (EVOO), the hallmark of the Mediterranean diet, on postprandial glycemic and lipid profile in healthy and pre-diabetic adults. In parallel, this group discovered incretin regulation as a plausible underlying mechanism for EVOO antioxidant and cardioprotective effects.
Despite robust clinical evidence associating the Mediterranean diet, especially its key component extra virgin olive oil (EVOO), with a lower risk of vascular disease, until now there has been no clear indication how it can exert its vascular protective effects. Furthermore, postprandial glycemia has been linked to higher prevalence of cardiovascular outcomes in the general population.
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